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Maxion Bags ÂŁ58M - A Game-Changer in Biotech

This is Cliff Equity, the UKâs business newsletter that keeps you informed on whatâs important in tech, business and finance in less than 5 minutes
In todayâs stories:
Supermarket Showdown: Asda Sparks Price War
Maxion Bags ÂŁ58M - A Game-Changer in Biotech
Trustpilot Trusts Itself: Revenue Jumps 19%!

The summary: The UK supermarket sector is in for a right old shake-up, as Asdaâs price-slashing gamble sends stocks tumbling, rivals scrambling, and investors wondering whether this is a savvy comeback or just a very expensive trolley dash.
The details:
Supermarket Sweep (of Value): Tesco, Sainsburyâs, and M&S have collectively lost over ÂŁ4bn in market value, as Asdaâs vow to slash prices sends investors running for the exits. Tesco took the biggest tumble, dropping 12%âperhaps not quite the ârollbackâ they had in mind.
The Cost of Cutting Costs: Asda is throwing cash at price cuts and extra staff in a bid to win back customers, but analysts arenât convinced they have the firepower to sustain the fight. Meanwhile, Tesco is giving shopworkers a pay riseâthough Sunday shift bonuses are getting the chop.
Price War or Price Wobble? Analysts fear a full-blown price war could hammer profits at the big players. But Tesco and Sainsburyâs, with their broader customer bases and beefier balance sheets, are better positioned to take on Asdaâs discounting spree.
Asdaâs Long Road to Redemption: New chairman Allan Leighton has a âsignificant war chestâ to fix years of sluggish sales, but with a reluctant supply chain and rivals circling like hungry vultures, the turnaround might take five yearsâif it happens at all.
Why it matters: When ÂŁ4bn vanishes from supermarket stocks faster than a yellow-stickered meal deal at 7pm, itâs a sign that investors are spooked by an impending price warâone that could squeeze profits and shake up the grocery pecking order. Asdaâs bargain bin battle plan might lure back shoppers, but if they canât shift enough volume, theyâll just be torching their own margins while Tesco and Sainsburyâs brace for impact. With rising wages, reluctant suppliers, and a competitive landscape sharper than a Waitrose cheddar, the next few months could decide whoâs feasting and whoâs left fighting over the scraps.

The summary: Maxion Therapeutics is on a mission to crack one of biotechâs toughest challengesâdeveloping antibody drugs for ion channels and GPCRsâwith its game-changing KnotBody technology, backed by ÂŁ58M in fresh funding and a team of scientific trailblazers.
The details:
A Scientific Snag No More â Despite their precision, antibodies have long struggled to target ion channels and GPCRsâuntil Maxion Therapeutics stepped in with its KnotBody platform, a clever fusion of antibodies and knottins to crack the code on these tricky proteins.
A Cash Injection with Clout â Maxion just pocketed a hefty ÂŁ58M in Series A funding, led by General Catalyst and joined by big names like British Patient Capital and Eli Lilly. A ÂŁ2M boost from Innovate UK further fuels its mission to revolutionise autoimmune disease treatments.
Cambridgeâs Biotech Brainpower â Founded in 2020 by antibody engineering pioneers Dr. John McCafferty and Dr. Aneesh Karatt-Vellatt, Maxion is taking a Nobel Prize-worthy approach to tackling diseases with historically elusive targets.
A Potential Game-Changer â With its lead program, MAX001, targeting inflammatory diseases and a pipeline brewing for pain and cardiovascular conditions, Maxionâs KnotBody tech could reshape drug development and redefine antibody therapeutics.
Why it matters: For years, scientists have struggled to design antibody drugs for ion channels and GPCRsâkey players in diseases from chronic pain to autoimmune disordersâleaving patients stuck with less effective, side-effect-ridden treatments. Maxionâs KnotBody technology could finally crack this puzzle, offering precision-engineered therapies where traditional drugs fall short. With ÂŁ58M in fresh funding and a team that practically wrote the book on antibody innovation, Maxion might just turn one of biotechâs toughest challenges into its next big breakthrough.

The summary: Trustpilot's soaring revenue, clever AI innovations, and booming business bookings are solidifying its place as the go-to platform for building trust, with plenty more growth and product upgrades on the horizon!
The details:
Trustpilotâs revenue surged 19% to $210m (ÂŁ161m), with earnings climbing 55%, thanks to a strong business adoption and brand awareness "fueling the flywheel."
Share price jumped 13% in early trades, and bookings grew 26% to $239m (ÂŁ184m)âproof that businesses are keen to pay for those handy reviews.
The companyâs freemium model is thriving, and the new AI-driven features, like market insights, are impressing customers who are willing to upgrade.
With plans for more share buybacks (up to ÂŁ20m) and product innovation, Trustpilot is reaping the benefits of scale and preparing for another year of solid growth.
Why it matters: Trustpilotâs impressive revenue and bookings growth show that businesses are increasingly willing to pay for reviews that boost their credibility. With consumers posting more reviews and Trustpilotâs clever use of AI, itâs clear the platform is making itself indispensable for businesses looking to build trust. Expect more share buybacks, product upgrades, and a growing dominance in the review worldâbecause letâs face it, everyone trusts a good review, especially when itâs backed by numbers.
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